The MGEA5 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to O-GLCNACASE, and OGA. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The MGEA5 antibody has been validated for the following applications: EIA, Immunoassay, Precipitation, ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Isoform 1: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc(in vitro)(PubMed:11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity(PubMed:24088714). Isoform 3: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc(in vitro), but has about six times lower specific activity than isoform 1